Dextromethorphan/Bupropion (45mg/105mg) Sustained Release Combination Capsules #30. DM/BUP is arguably one of the most exciting antidepressant combinations, soon to be FDA approved, for multiple indications including Alzheimer's agitation, smoking cessation, and depression/anxiety disorders. Dextromethorphan-an NMDA receptor agonist which works on the brain much like Ketamine, has long been clinically studied to work as an acute depression treatment, often working in as little as a few hours to days. Many patients who are feeling depression symptoms, loss of pleasure, frustration and confusion in our post COVID 19 pandemic world may benefit from a short course of this novel drug therapy. Exclusively available through National Wellness Doctors, this important drug combination is not available anywhere in the world that we know of. Get your virtual consult done for FREE and have this med shipped to your door!